Table 3.
Mouse Strain | Human Cells | Number of Mice Evaluated |
---|---|---|
NSG | Transduced hCD34+ HSCs | 5 |
NSG | Leukemia B-ALL PDX, derived from 15 patients | 18 |
NSG-SGM3 | Naïve | 3 |
NSG-SGM3 | Humanized, hCD34+ HSCs | 14 |
NSG-SGM3 | Transduced hCD34+ HSCs | 3 |
NSG-SGM3 | Leukemia AEL PDX, derived from 3 patients | 8 |
NRG-SGM3 | Leukemia AML PDX, derived from 1 patient | 16 |
Abbreviations: HSCs, hematopoietic stem cells; AEL, acute erythroid leukemia; PDX, patient derived xenograft; AML, acute myeloid leukemia