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. 2021 Aug 15;11(8):3893–3906.

Table 2.

List of common genes in different pathways

Pathways Genes
PI3K-AKT AKT3, TSC2, PTEN, mTOR, PIK3CA, RPTOR, TSC1, TCS2, RICOTR, PI3K3R2, PI3K3CB, INPP4B, STK11, PPP2R1A, PIK3R1, AKT2, RHEB, PDK1, AKT1
RAS/MAPK KRAS, MAP2K1, NF1, NF2
Wnt/β-catenin AXIN1, AXIN2, RNF43, WNT7B, WNT108, AMER1, CHD4, TCF7L2, WNT10A
Cell cycle TP53, TERT, CTNNB1, ATM, APC, CDK4, CCND1, CCND3, CCND2, CDKN2A, RB1, CCNE1, CDK6, CDK8, CCKN2A/B, CDKN1B CDKN2B
DNA repair ATR, ATM, BACA1, BRCA2, MLH1, MSH2, MSH6, FANCA, BRIP1, BAP1, CHEK2, ERCC2, FANCA/D2/E/L, MUTYH, NBN, PMS2, RAD50/51B, WRN
Transcriptome IGF1R, RET, ERBB2, EGFR, KIT, PDGFRA, KDR, ERBB4, FLT4, PDGFRB, MET, FLT3, ERBB3
Growth factor receptors MYC, SOX2, KDM6A, SMARCA4, RUNX1, MYCN, EZH2, NKX2, KMT2D, SMARCB1, DNMT3A, MYCL1, SOX10, ARID2, ASXL1, DNMT3A, EP300, KMT2C, KMT2D, NSD3, PBRM1, SMARCB1, SETD2, BAP1, IDH1, IDH2