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Brain organoids models display hallmarks of neurodevelopmental and neurodegenerative diseases. Time in culture (months) of hallmarks and functional alterations observed in organoids modeling brain disorders are depicted. Neurodevelopmental disorders include microcephaly by viral infection (Zika virus), Autism and Rett's syndrome. Neurodegenerative diseases include Parkinson's and Alzheimer's, and viral infection by SARS-CoV2.
