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. 2021 Aug 13;12:687335. doi: 10.3389/fgene.2021.687335

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Copyright © 2021 Dlamini, Choudhury, Ramsay, Micklesfield, Norris, Crowther, Crawford, Walker, Lombard and Goedecke.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Allele frequencies for SERPINA6/A1 rs17090691-G (A) and rs1051052-G (B) variants in the present study sample (n = 4,431) and other global populations. Minor allele frequencies from the other populations were obtained from the 1,000 Genomes Project phase 3 dataset. Other Africans include Yoruba in Ibadan (Nigeria), Luhya in Webuye (Kenya), Gambian in Western Divisions (Gambia), Mende (Sierra Leone), Esan (Nigeria), Americans of African Ancestry in SW (United States), and African Caribbeans (Barbados). Europeans include Utah Residents (CEPH) with Northern and Western European Ancestry, Toscani (Italy), Finnish (Finland), British (England and Scotland), and Iberian Population (Spain). Americans include Mexican Ancestry from Los Angeles (United States), Puerto Ricans (Puerto Rico), Colombians from Medellin (Colombia), and Peruvians from Lima (Peru). East Asians include Han Chinese in Beijing (China), Japanese in Tokyo (Japan), Southern Han Chinese, Chinese Dai in Xishuangbanna (China), and Kinh in Ho Chi Minh City (Vietnam). South Asians include Gujarati Indian from Houston (Texas), Punjabi from Lahore (Pakistan), Bengali (Bangladesh), Sri Lankan Tamil (the United Kingdom), and Indian Telugu (the United Kingdom).