Table 3.
Clinical characteristics of Clinical hypoPT
| Index | No hypoPT (N = 1043) | Transient hypoPT (N = 72) | Permanent hypoPT (N = 55) | P1 | P2 |
|---|---|---|---|---|---|
| Age | 41.06 ± 11.05 | 41.88 ± 13.45 | 40.89 ± 13.37 | 0.615 | 0.683 |
| ≥ 55 years | 109 (10.5) | 15 (20.8) | 9 (16.4) | 0.007* | 0.524 |
| Gender | |||||
| Male | 333 (31.9) | 16 (22.2) | 13 (23.6) | 0.086 | 0.851 |
| Female | 710 (68.1) | 56 (77.8) | 42 (76.4) | 0.086 | 0.851 |
| 131I | 546 (52.3) | 38 (52.8) | 36 (65.5) | 0.944 | 0.151 |
| BMI | 23.23 ± 4.12 | 23.29 ± 3.06 | 23.07 ± 3.88 | 0.910 | 0.728 |
| > 24 | 376 (36.6) | 29 (42.0) | 18 (32.7) | 0.364 | 0.289 |
| Hypertension | 84 (8.1) | 6 (8.3) | 3 (5.5) | 0.933 | 0.731 |
| Diabetes | 31 (3.0) | 2 (2.8) | 2 (3.6) | 1 | 1 |
| Hypothyroidism | 14 (1.3) | 1 (1.4) | 1 (1.8) | 1 | 1 |
| Hyperthyroidism | 27 (2.6) | 1 (1.4) | 0 (0) | 1 | 1 |
| HD | 229 (22.0) | 12 (16.7) | 15 (27.3) | 0.292 | 0.148 |
| NG | 541 (51.9) | 31 (43.1) | 30 (54.5) | 0.148 | 0.199 |
| Pre PTH | 4.96 ± 1.10 | 4.91 ± 1.19 | 4.82 ± 1.10 | 0.698 | 0.673 |
| Pre Ca | 2.35 ± 0.14 | 2.32 ± 0.10 | 2.32 ± 0.10 | 0.042* | 0.925 |
| Pre Mg | 0.89 ± 0.09 | 0.91 ± 0.18 | 0.88 ± 0.08 | 0.192 | 0.305 |
| Pre P | 1.12 ± 0.20 | 1.12 ± 0.20 | 1.14 ± 0.17 | 0.893 | 0.508 |
| Pre 25-OH-VD | 45.81 ± 17.02 | 46.79 ± 16.08 | 48.53 ± 27.66 | 0.759 | 0.788 |
| Carbon nanoparticles | 787 (75.5) | 45 (62.5) | 41 (74.5) | 0.015* | 0.150 |
| Unintentionally resected PGs | 0.09 ± 0.35 | 0.08 ± 0.28 | 0.13 ± 0.34 | 0.799 | 0.422 |
| ≥ 1PG | 83 (8.0) | 6 (8.3) | 7 (12.7) | 0.909 | 0.418 |
| Autotransplanted PGs | 0.99 ± 0.77 | 1.29 ± 0.70 | 1.13 ± 0.70 | 0.001* | 0.191 |
| No PG | 298 (28.6) | 9 (12.5) | 8 (14.5) | 0.003* | 0.737 |
| 1 PG | 474 (45.4) | 34 (47.2) | 34 (61.8) | 0.770 | 0.102 |
| ≥ 2PGs | 271 (26.0) | 29 (40.3) | 13 (23.6) | 0.008* | 0.048* |
| Neck dissection | |||||
| UCND | 277 (26.6) | 6 (8.3) | 7 (12.7) | 0.001* | 0.418 |
| BCND | 766 (73.4) | 66 (91.7) | 48 (87.3) | 0.001* | 0.418 |
| ULND | 184 (17.6) | 16 (22.2) | 14 (25.5) | 0.327 | 0.671 |
| BLND | 21 (2.0) | 4 (5.6) | 2 (3.6) | 0.072 | 0.697 |
| Intraoperative blood loss (mL) | 44.25 ± 41.11 | 69.49 ± 111.98 | 62.10 ± 87.73 | 0.069 | 0.699 |
| Intraoperative liquid infusion (mL) | 1330 ± 700 | 1526 ± 705 | 1678 ± 829 | 0.028* | 0.295 |
| Tumor characteristics | |||||
| Isthmus | 48 (4.8) | 10 (14.3) | 2 (3.6) | 0.001* | 0.065 |
| Multifocality | 142 (14.1) | 20 (28.2) | 18 (32.7) | 0.430 | 0.696 |
| Bilaterality | 245 (24) | 11 (15.7) | 13 (23.6) | 0.716 | 0.264 |
| Capsular invasion | 227 (21.8) | 8 (11.1) | 14 (25.5) | 0.032* | 0.034* |
| Minor ETE | 95 (9.1) | 7 (55.6) | 3 (5.5) | 0.863 | 0.512 |
| Major ETE | 56 (5.4) | 4 (9.7) | 4 (7.2) | 0.792 | 0.726 |
BMI, Body mass index; HD, Hashimoto’s thyroiditis; NG, Nodular goiter; Pre, preoperative; PTH, Parathyroid Hormone; Ca, calcium; Mg, Magnesium; P, phosphorus; PG, Parathyroid Gland; UCND, unilateral central neck dissection; BCND, bilateral central dissection; ULND, unilateral lateral neck dissection; BLND, bilateral lateral neck dissection; ETE, extrathyroidal extension
*P < 0.05