Table 3.
Arms | Classification of acute toxic reactions | Number of cases (%) | χ2 | P | |||||
---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | |||||
leukopenia | Control | 15 | 8 | 13 | 4 | 3 | 28 (65.12%). | 1.062 | 0.303 |
Experimental | 12 | 14 | 16 | 6 | 0 | 36 (75.00%). | |||
Neutropenia | Control | 24 | 5 | 7 | 3 | 4 | 19 (44.19%). | 5.588 | 0.018 |
Experimental | 15 | 18 | 9 | 5 | 1 | 33 (68.75%). | |||
thrombocytopenia | Control | 30 | 9 | 2 | 1 | 1 | 13 (30.23%). | 0.276 | 0.599 |
Experimental | 31 | 12 | 5 | 0 | 0 | 17 (35.42%). | |||
Blood in the urine | Control | 22 | 14 | 6 | 0 | 1 | 21 (48.84%). | 0.008 | 0.930 |
Experimental | 25 | 16 | 6 | 1 | 0 | 23 (47.92%). | |||
proteinuria | Control | 32 | 6 | 4 | 1 | 0 | 11 (25.58%). | 0.653 | 0.419 |
Experimental | 32 | 12 | 4 | 0 | 0 | 16 (33.33%). | |||
hypertension | Control | 42 | 1 | 0 | 0 | 0 | 1 (2.33%). | 0.032* | |
Experimental | 40 | 8 | 0 | 0 | 0 | 8 (16.67%) | |||
bleeding | Control | 34 | 7 | 2 | 0 | 0 | 9 (20.93%) | 0.212 | 0.645 |
Experimental | 36 | 11 | 1 | 0 | 0 | 12 (25.00%). | |||
infection | Control | 35 | 4 | 2 | 2 | 0 | 8 (18.60%) | 9.806 | 0.02 |
Experimental | 24 | 16 | 8 | 0 | 0 | 24 (50.00%). | |||
nausea | Control | 17 | 12 | 12 | 2 | 0 | 26 (60.47%). | 3.957 | 0.046 |
Experimental | 29 | 9 | 10 | 0 | 0 | 20 (41.67%). | |||
vomiting | Control | 28 | 8 | 5 | 2 | 0 | 15 (34.88%). | 1.062 | 0.303 |
Experimental | 36 | 7 | 5 | 0 | 0 | 12 (25.00%). | |||
diarrhea | Control | 32 | 6 | 2 | 3 | 0 | 11 (25.58%). | 0.026 | 0.871 |
Experimental | 35 | 10 | 3 | 0 | 0 | 13 (27.08%). | |||
Skin damage* | Control | 34 | 8 | 0 | 0 | 1 | 9 (20.93%) | 0.052 | 0.819 |
Experimental | 37 | 10 | 1 | 0 | 0 | 11 (22.92%). | |||
Lower alimentary canal and pelvic cavity* | Control | 35 | 5 | 2 | 1 | 0 | 8 (18.60%) | 3.217 | 0.073 |
Experimental | 31 | 8 | 8 | 0 | 1 | 17 (35.42%). | |||
Genitourinary tract* | Control | 40 | 0 | 2 | 0 | 1 | 3 (6.98%) | 0.323* | |
Experimental | 41 | 5 | 1 | 1 | 0 | 7 (14.58%) | |||
Radiation cystitis* | Control | 42 | 0 | 0 | 0 | 1 | 1 (2.33%). | 1.00* | |
Experimental | 46 | 1 | 0 | 1 | 0 | 2 (4.17%). | |||
Radiation proctitis* | Control | 38 | 3 | 1 | 1 | 0 | 5 (11.63%) | 0.173 | 0.677 |
Experimental | 41 | 1 | 5 | 0 | 1 | 7 (14.58%) |
*denotes radiation-related injury.