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. 2021 Aug 13;11:723193. doi: 10.3389/fonc.2021.723193

Table 5.

Comparison of blood indicators and VEGF-A between the two groups before and after treatment.

Indicators Arms Before the treatment After treatment Z/t P value
Routine indexes (Unit) WBC (x 109/L) Control *5.29 (3.89, 6.7) *4.11 (3.09, 4.64) 3.592 <0.001
Experimental ^4.230 ± 1.67 ^4.70 ± 2.11 1.029 0.309
HB (g/L) Control *111.00 (102.00, 122.00) *106.00 (100.00, 116.00) 3.177 0.001
Experimental ^113.02 ± 15.68 ^107.00 ± 12.64 3.092 0.003
PLT (x 109/L) Control ^244.00 ± 103.84 ^184.62 ± 70.25 4.226 <0.001
Experimental ^174.52 ± 63.16 ^158.60 ± 51.98 1.684 0.099
ALB (g/L) Control *41.20 (38.10, 42.70) *39.90 (37.10, 42.60) 1.357 0.175
Experimental *42.75 (40.25, 44.85) *41.40 (38.05, 43.60) 2.101 0.36
Tumor indexes (Unit, reference value) SCC (ng/L, 0-3.00) Control *4.45 (2.17, 8.20) *1.72 (0.80, 5.10) 3.900 <0.001
Experimental *3.29 (1.27, 6.46) *1.20 (0.77, 2.08) 5.143 <0.001
CEA (ng/ml, 0-5.00) Control *3.12 (2.10, 5.10) *1.90 (1.3, 4.30) 2.857 0.004
Experimental *2.86 (1.43, 5.10) *1.68 (1.10, 2.78) 5.208 <0.001
CYRA21-1(ng/ml, 0-3.30) Control *3.02 (2.19, 4.07) *2.07 (1.56, 2.88) 2.702 0.007
Experimental *3.01 (1.74, 3.93) *2.16 (1.47, 3.15) 3.069 0.002
VEGF-A (pg/ml) Control +285.44 ± 53.25 +264.18 ± 49.24 4.183 <0.001
Experimental  295.64 ± 73.44  273.13 ± 65.60 3.030 0.004

*Median and quaternary values (P25, P75). ^mean ± standard deviation.

+Before and after treatment, t test was used to analyze VEGF-A levels in the two groups, and there was no statistical difference between the two groups (P > 0.05).