Table 2.
Etiology of Pneumonia and Pleural Effusion Based on Culture and/or Polymerase Chain Reaction Among Children <15 Years Old in Santo Domingo, Dominican Republic
| Pathogens Detected by Culture and/or PCRa | Cases, % (No.)b | P Value | |
|---|---|---|---|
| Pre-PCV13 (n = 94) |
Post-PCV13 (n = 248)c |
||
| Streptococcus pneumoniae | 56.4 (53) | 52.8 (131) | .55 |
| Staphylococcus aureus | 16.0 (15) | 16.5 (41) | .90 |
| Haemophilus influenzae | 11 (10)d | 5.2 (13) | .05 |
| Streptococcus pyogenes | 1.1 (1) | 1.21 (3) | 1.0 |
| Other | 0 | 7.3 (18)e | <.01 |
| No cause determined | 27.7 (26) | 24.6 (61) | .56 |
Abbreviations: PCR, polymerase chain reaction; PCV13, 13-valent pneumococcal conjugate vaccine.
aPathogens were not mutually exclusive.
bData represent % (no.) of cases, unless otherwise identified.
cIncludes 30 cases captured in surveillance with only laboratory information available.
dFive cases were unavailable for H. influenzae testing (n = 89).
eIncluding 3 cases of Serratia marcenses, 3 of Pseudomonas aeruginosa, 2 of Acinetobacter spp., 2 of Enterobacter cloacae, 2 of Klebsiella pneumoniae, 2 of Escherichia coli, and 4 Streptococcus spp.