Figure 5.
Knockdown of XPOT inhibits neuroblastoma cell proliferation and migration. (A) RT-qPCR identifies the efficiency of siRNA against XPOT in SK-N-BE(2), SH-SY5Y, and SK-N-SH cells. (B) Western blot identifies the knockdown efficiency of siRNA against XPOT. (C) A CCK-8 array indicates the relative growth of SK-N-BE(2), SH-SY5Y, and SK-N-SH cells after knockdown by siRNA against XPOT. (D) Colony images and histogram for SK-N-BE(2), SH-SY5Y, and SK-N-SH cell lines after knockdown of XPOT. (E) Cell migration images and histogram for SK-N-BE(2), SH-SY5Y, and SK-N-SH cell lines after knockdown of XPOT. All experiments were performed 3 times independently. Error bars represent the mean ± SD. * P < .05.
Abbreviations: XPOT, Exportin-T; RT-qPCR, quantitative real-time- polymerase chain reaction.