Table 1.
Association Between XPOT mRNA Expression and Clinical Characteristics in Neuroblastoma Patients (SEQC).
| XPOT expression | ||||
|---|---|---|---|---|
| Factors | Cases No. | low, No. (%) | high, No. (%) | P value |
| Gender | .544 | |||
| female | 211 | 188 (89.1) | 23 (10.9) | |
| male | 287 | 261 (90.9) | 26 (9.1) | |
| Age (month) | <.001 | |||
| ≤18 | 300 | 287 (95.7) | 13 (4.3) | |
| >18 | 198 | 162 (81.8) | 36 (18.2) | |
| MYCN amplification | <.001 | |||
| No | 401 | 388 (96.8) | 13 (3.2) | |
| Yes | 92 | 57 (62.0) | 35 (38.0) | |
| Tumor stage (INSS) | <.001 | |||
| 4s + 1 + 2 | 252 | 247 (98.0) | 5 (2.0) | |
| 3 + 4 | 246 | 202 (82.1) | 44 (17.9) | |
| High risk | <.001 | |||
| No | 322 | 317 (98.5) | 5 (1.5) | |
| Yes | 176 | 132 (75.0) | 44 (25.0) | |
| Progression | <.001 | |||
| No | 315 | 307 (97.5) | 8 (2.5) | |
| Yes | 183 | 142 (77.6) | 41 (22.4) | |
| Death | <.001 | |||
| No | 393 | 377 (95.9) | 16 (4.1) | |
| Yes | 105 | 72 (68.6) | 33 (31.4) | |
Pearson's χ2 test was used for statistical analysis.
Abbreviations: INSS, International Neuroblastoma Staging System; XPOT, Exportin-T; SEQC, Sequencing Quality Control Consortium.