Table 2.
Group mean value of shear wave speed c in all 80 patients and collagen volume fraction (CVF) in a subgroup of 69 patients by pathology-based TN stage, LVI and PNI status, degree of tumor differentiation, prognostic stage, and risk level of all patients.
| Prognostic factor | No. of patients (total n=80) | Shear wave speed c (m/s) | p value | No. of patients (total n=69) | CVF | p value |
|---|---|---|---|---|---|---|
| pT stage | <0.0001 | 0.0086 | ||||
| pT1-2 | 32 | 2.0 ± 0.4 | 27 | 0.13 ± 0.11 | ||
| pT3-4 | 48 | 2.4 ± 0.5 | 42 | 0.21 ± 0.12 | ||
| pN stage | 0.013 | <0.0001 | ||||
| pN0 | 54 | 2.2 ± 0.6 | 45 | 0.12 ± 0.091 | ||
| pN1-2 | 26 | 2.5 ± 0.4 | 24 | 0.29 ± 0.097 | ||
| LVI | 0.017 | 0.1675 | ||||
| Negative | 68 | 2.2 ± 0.5 | 57 | 0.17 ± 0.12 | ||
| Positive | 12 | 2.6 ± 0.5 | 12 | 0.23 ± 0.12 | ||
| PNI | 0.018 | 0.0269 | ||||
| Negative | 72 | 2.2 ± 0.5 | 61 | 0.17 ± 0.12 | ||
| Positive | 8 | 2.7 ± 0.5 | 8 | 0.27 ± 0.11 | ||
| Degree of tumor differentiation | 0.040 | 0.0007 | ||||
| Well to moderately differentiated | 71 | 2.2 ± 0.5 | 62 | 0.17 ± 0.11 | ||
| Poorly differentiated | 9 | 2.6 ± 0.5 | 7 | 0.32 ± 0.084 | ||
| Prognostic stage | 0.0022 | <0.0001 | ||||
| Stage 0-I | 26 | 1.9 ± 0.5 | 22 | 0.010 ± 0.082 | ||
| Stage II-III | 27 | 2.3 ± 0.6 | 20 | 0.15 ± 0.085 | ||
| Stage III-IV | 27 | 2.5 ± 0.4 | 27 | 0.27 ± 0.11 | ||
| Risk stratification | <0.001 | <0.001 | ||||
| Low-risk | 44 | 2.1 ± 0.5 | 37 | 0.11 ± 0.08 | ||
| High-risk | 36 | 2.5 ± 0.5 | 32 | 0.27 ± 0.10 |
CVF, collagen volume fraction; LVI, lymphovascular invasion, PNI, perineural invasion. Prefix p in the stages represents pathology.