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. 2021 Aug 13;11:701336. doi: 10.3389/fonc.2021.701336

Table 4.

Contingency analysis of c, MRI, and combined MRI and c for predicting pT3-4 and pN1-2 using histopathology as reference standard.

Overall accuracy (%) Weighted Kappa (95%CI) Sensitivity (%) Specificity (%) PPV (%) NPV (%)
Predicting pT1-2 ( 40 ) vs pT3-4(+)
MRI 96 (77/80) 0.92 (0.83-1.00) 98 (47/48) 94 (30/32) 96 (47/49) 97 (30/31)
c 76 (61/80) 0.49 (0.29-0.68) 88 (42/48) 59 (19/32) 76 (42/55) 76 (19/25)
MRI + c 96 (77/80) 0.92 (0.83-1.00) 98 (47/48) 94 (30/32) 96 (47/49) 97 (30/31)
Predicting pN0 ( 40 ) vs pN1-2(+)
MRI 74 (59/80) 0.49 (0.32-0.66) 92 (24/26) 65 (35/54) 56 (24/43) 95 (35/37)
c 68 (54/80) 0.38 (0.21-0.56) 88 (23/26) 57 (31/54) 50 (23/46) 91 (31/34)
MRI + c 84 (67/80) 0.65 (0.47-0.82) 85 (22/26) 83 (45/54) 71 (22/31) 92 (45/49)

Prefix p in the stages represents pathology. PPV, positive predictive value; NPV, negative predictive value.