PMP (disseminated peritoneal adenomucinosis [DPAM]) in a 50-year-old man
with progressive abdominal distention, early satiety, and weight loss
due to a ruptured low-grade appendiceal mucinous neoplasm (LAMN).
(a, b) Axial (a) and coronal
(b) T2-weighted images show heterogeneously
T2-hyperintense mucin (arrowheads) surrounding the liver and stomach,
with subcapsular splenic implants (* in a). Close
examination of the coronal image shows marked distention of the appendix
(arrow in b) with a “pear” or “chicken
drumstick” appearance. (c) Photograph of the cut
resected spleen shows subcapsular splenic implants (*), which
correlate with those seen at MRI. (d) Low-power
photomicrograph of the appendix (H-E stain) shows loss of the normal
mucosal architecture with proliferation of columnar mucinous epithelial
cells (arrowhead), which produce mucinous content. The mucin (*)
distends the appendiceal lumen and dissects through the ruptured wall
(arrows), where it implanted diffusely along the peritoneal surface,
leading to PMP.