Schematic diagram of the structure of fusion (MFN1, MFN2, OPA1) and fission (DRP1) regulators. MFN1- Mitofusin 1, MFN2- Mitofusin 2, OPA1- Optic atrophy protein 1, DRP1- Dynamin related protein 1, TM- transmembrane, PR- proline rich, HR1- helical repeat 1, HR2- helical repeat 2, N- N terminal, C- C terminal, MTS- mitochondrial targeting sequence, BSE- bundle signaling element.