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. 2021 Aug 13;9:714787. doi: 10.3389/fcell.2021.714787

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Copyright © 2021 Ghafouri-Fard, Azimi, Hussen, Abak, Taheri and Dilmaghani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A schematic summary of the crosstalk between the RhoA/ROCK1 singling pathway and lncRNA NORAD in gastric cancer. The figure depicts the impact of RhoA/ROCK1 involved in LIMK/cofilin/TRPV4/Ca2+ pathway in gastric cancer. LncRNA NORAD could promote the expression levels of RhoA and ROCK1, and thereby enhancing cell proliferation, migration and invasiveness and reducing cell apoptosis in gastric cancer cells (Yu et al., 2019).