Table 1.
First author, year | Tumor types | Study design | Treatment arms | Sample size | Age | Gender | Efficacy outcomes reported | Safety outcomes reported |
---|---|---|---|---|---|---|---|---|
Liu et al. (22) | Relapsed/refractory Hodgkin lymphoma | Randomized phase II study | Camrelizumab | 19 | 28 (18–44) | 12/7 | PFS, duration of response (DOR), ORR | Any grade, Grade 3–4 |
Chemotherapy (Decitabine)+ camrelizumab | 42 | 26 (12–66) | 25/17 | |||||
Zhou et al. (23) | Advanced non-squamous non-small-cell lung cancer (CameL) |
Randomized, open-label, multicenter, phase III trial | Camrelizumab+ Chemotherapy (carboplatin+ pemetrexed) |
205 | 59 (54–64) | 146/59 | PFS, OS, ORR | Any grade, Grade 3–4 |
Chemotherapy (carboplatin+ pemetrexed) |
207 | 61 (53–65) | 149/58 | |||||
Huang et al. (24) | Advanced or metastatic esophageal squamous cell carcinoma (ESCORT) | Multicenter, randomized, open-label, phase III study | Camrelizumab group | 228 | 60 (54–65) | 208/20 | OS, PFS, DOR, ORR | Any grade, Grade 3–4 |
Chemotherapy group | 220 | 60 (54–65) | 192/28 | |||||
Nie et al. (25) | Relapsed/refractory Classical Hodgkin Lymphoma |
Two-arm, open-label, phase II study | Camrelizumab | 19 | ORR | Any grade, Grade 3–4 | ||
Chemotherapy (Decitabine)+ camrelizumab | 25 |