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. 2021 Aug 9;11:700165. doi: 10.3389/fonc.2021.700165

Table 1.

Baseline Characteristic of included studies.

First author, year Tumor types Study design Treatment arms Sample size Age Gender Efficacy outcomes reported Safety outcomes reported
Liu et al. (22) Relapsed/refractory Hodgkin lymphoma Randomized phase II study Camrelizumab 19 28 (18–44) 12/7 PFS, duration of response (DOR), ORR Any grade, Grade 3–4
Chemotherapy (Decitabine)+ camrelizumab 42 26 (12–66) 25/17
Zhou et al. (23) Advanced non-squamous non-small-cell lung cancer
(CameL)
Randomized, open-label, multicenter, phase III trial Camrelizumab+
Chemotherapy (carboplatin+
pemetrexed)
205 59 (54–64) 146/59 PFS, OS, ORR Any grade, Grade 3–4
Chemotherapy (carboplatin+
pemetrexed)
207 61 (53–65) 149/58
Huang et al. (24) Advanced or metastatic esophageal squamous cell carcinoma (ESCORT) Multicenter, randomized, open-label, phase III study Camrelizumab group 228 60 (54–65) 208/20 OS, PFS, DOR, ORR Any grade, Grade 3–4
Chemotherapy group 220 60 (54–65) 192/28
Nie et al. (25) Relapsed/refractory
Classical Hodgkin Lymphoma
Two-arm, open-label, phase II study Camrelizumab 19 ORR Any grade, Grade 3–4
Chemotherapy (Decitabine)+ camrelizumab 25