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. 2021 Aug 16;12:666300. doi: 10.3389/fgene.2021.666300

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Copyright © 2021 Ge, Hua, Chen, Xiao, Zhang, Zhou, Liang and Tai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Consensus clustering based on the five costimulatory molecule genes. (A) Consensus clustering cumulative distribution function (CDF) for k = 2 to k = 10. (B) The relative change in area under the CDF curve for k = 2 to k = 10. (C) The Kaplan–Meier curve evaluate the prognosis of prostate cancer patients. (D) The Gene Set Enrichment Analysis showed that several oncogenic pathways were significantly enriched in cluster 1.