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. 2021 Aug 16;12:666300. doi: 10.3389/fgene.2021.666300

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Copyright © 2021 Ge, Hua, Chen, Xiao, Zhang, Zhou, Liang and Tai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The association between the expression levels of the five costimulatory molecules and clinical factors. (A) The expression levels of the five costimulatory molecules between the normal and tumor samples; (B) T2 staging vs. T3 and T4 staging; (C) N0 staging vs. N1 staging. (D) Gleason score for 6, 7, 8, 9, and 10. GS represents the Gleason score. The unpaired Student’s t-test was performed for comparison between two samples and the one-way analysis of variance test for comparison between multiple samples.