TABLE 1.
Univariate Cox analysis of costimulatory molecule genes in TCGA dataset.
| Official symbol | HR | P-value | HR.95L | HR.95H |
| RELT | 1.649 | <0.001 | 1.319 | 2.061 |
| TNFRSF25 | 1.418 | <0.001 | 1.196 | 1.682 |
| EDA2R | 0.746 | <0.001 | 0.635 | 0.877 |
| TNFSF18 | 1.703 | <0.001 | 1.269 | 2.284 |
| TNFRSF18 | 1.321 | 0.001 | 1.129 | 1.546 |
| CD80 | 1.317 | 0.002 | 1.107 | 1.567 |
| CD276 | 1.652 | 0.002 | 1.196 | 2.284 |
| LTA | 1.277 | 0.005 | 1.080 | 1.510 |
| TNFRSF6B | 1.346 | 0.005 | 1.095 | 1.656 |
| CD86 | 1.336 | 0.006 | 1.087 | 1.641 |
| TNFSF10 | 0.742 | 0.015 | 0.584 | 0.943 |
| LTBR | 0.572 | 0.018 | 0.360 | 0.908 |
| CD70 | 1.243 | 0.027 | 1.025 | 1.507 |
| TNFSF13 | 0.699 | 0.037 | 0.499 | 0.979 |
| LTB | 1.135 | 0.051 | 0.100 | 1.289 |
| TNFRSF4 | 1.167 | 0.055 | 0.997 | 1.367 |
| TNFRSF8 | 1.207 | 0.072 | 0.983 | 1.482 |
| TNFRSF1B | 1.238 | 0.080 | 0.974 | 1.574 |
| TNFRSF10C | 0.859 | 0.080 | 0.724 | 1.019 |
| EDA | 1.186 | 0.086 | 0.976 | 1.440 |
| CTLA4 | 1.136 | 0.089 | 0.981 | 1.316 |
| TNFSF13B | 1.163 | 0.090 | 0.977 | 1.385 |
| FASLG | 1.136 | 0.144 | 0.957 | 1.348 |
| TNFSF15 | 0.911 | 0.150 | 0.803 | 1.034 |
| TNFRSF10D | 0.877 | 0.161 | 0.731 | 1.053 |
| ICOS | 1.108 | 0.164 | 0.959 | 1.280 |
| TNFSF14 | 1.136 | 0.179 | 0.943 | 1.369 |
| TNFRSF9 | 1.122 | 0.183 | 0.947 | 1.328 |
| TNFRSF10A | 0.873 | 0.188 | 0.714 | 1.069 |
| TNFSF11 | 1.150 | 0.200 | 0.928 | 1.426 |
| TNFRSF1A | 0.755 | 0.213 | 0.485 | 1.175 |
| TNFSF9 | 1.098 | 0.227 | 0.944 | 1.277 |
| TNFRSF12A | 1.089 | 0.316 | 0.922 | 1.287 |
| TNFRSF13B | 1.069 | 0.318 | 0.937 | 1.220 |
| TNFRSF17 | 1.071 | 0.323 | 0.935 | 1.227 |
| CD27 | 1.076 | 0.352 | 0.922 | 1.255 |
| NGFR | 0.935 | 0.370 | 0.807 | 1.083 |
| PDCD1 | 1.074 | 0.397 | 0.910 | 1.268 |
| FAS | 0.903 | 0.405 | 0.710 | 1.149 |
| TNFSF8 | 1.070 | 0.422 | 0.907 | 1.263 |
| TNFSF12 | 0.872 | 0.435 | 0.619 | 1.229 |
| TNFSF4 | 1.115 | 0.445 | 0.843 | 1.476 |
| TNF | 1.064 | 0.470 | 0.899 | 1.258 |
| HHLA2 | 0.944 | 0.500 | 0.799 | 1.115 |
| TNFRSF11A | 0.939 | 0.516 | 0.778 | 1.134 |
| ICOSLG | 1.114 | 0.552 | 0.800 | 1.592 |
| VTCN1 | 0.971 | 0.558 | 0.881 | 1.071 |
| TNFRSF13C | 1.056 | 0.565 | 0.877 | 1.271 |
| TNFRSF11B | 0.951 | 0.572 | 0.800 | 1.132 |
| TNFRSF10B | 0.897 | 0.585 | 0.607 | 1.326 |
| CD274 | 1.052 | 0.601 | 0.869 | 1.274 |
| TNFRSF21 | 1.066 | 0.612 | 0.833 | 1.364 |
| TNFRSF14 | 1.078 | 0.627 | 0.797 | 1.457 |
| TMIGD2 | 1.044 | 0.633 | 0.876 | 1.244 |
| EDAR | 1.030 | 0.634 | 0.911 | 1.165 |
| PDCD1LG2 | 1.023 | 0.817 | 0.842 | 1.245 |
| CD28 | 0.984 | 0.840 | 0.844 | 1.148 |
| TNFRSF19 | 1.009 | 0.899 | 0.882 | 1.153 |
| CD40 | 0.988 | 0.907 | 0.811 | 1.204 |
| CD40LG | 0.995 | 0.948 | 0.851 | 1.163 |
HR, hazard ratio; HR.95L, Lower limit of the 95% confidence interval; HR.95H, Upper limit of the 95% confidence interval.