Table 4.
Fetal HR, HR variability and movement (n = 148).
|
Control
( n = 57) |
Depressed
( n = 42) |
SRI-Depressed
( n = 31) |
SRI-Non-Depressed
( n = 18) |
|||||
|---|---|---|---|---|---|---|---|---|
| Fetal variables | AM | PM | AM | PM | AM/pre-dose | PM/post-dose | AM/pre-dose | PM/post-dose |
| Basal HR (bpm)a | 135 ± 7 | 136 ± 8 | 134 ± 7 | 137 ± 8 | 134 ± 9 | 138 ± 8 | 132 ± 9 | 139 ± 10 |
| HR accelerations (n)b | 14 (11, 18) | 16 (13, 20) | 16 (11, 20) | 15.5 (12, 19) | 12 (9, 15) | 14 (12, 17) | 14 (10, 18) | 13.5 (10, 15) |
| HR decelerations (n) | 1 (0, 1) | 1 (0, 2) | 0 (0, 2) | 1 (0, 2) | 1 (0, 2) | 1 (0, 2) | 1 (0, 2) | 2 (0.25, 3) |
| STV (ms)a | 10.4 ± 3.1 | 10.9 ± 2.9 | 10.9 ± 3.1 | 10.7 ± 3.0 | 10.6 ± 3.4 | 9.6 ± 2.4 | 11.5 ± 2.7 | 9.5 ± 2.1 |
| High HR variability (min)a | 30.0 ± 13.0 | 32.5 ± 11.9 | 31.2 ± 12.1 | 33.1 ± 11.2 | 30.3 ± 14.3 | 31.4 ± 11.0 | 34.9 ± 9.3 | 25.7 ± 12.4 |
| Low HR variability (min) | 0.97 ± 2.5 | 1.8 ± 4.1 | 1.7 ± 4.2 | 1.4 ± 4.0 | 1.5 ± 2.9 | 0.70 ± 2.2 | 0.50 ± 1.9 | 1.8 ± 4.4 |
| Fetal movements/hour (n)† | 50 (31, 66) | 53 (35, 82) | 53.5 (37, 77) | 57 (38, 86) | 46 (28, 62) | 47 (30, 69) | 43.5 (30, 83) | 60 (32, 83) |
Fetal variables for each group are summarized as mean ± SD if continuous and normally-distributed, or median (first, third quartile) if skewed or count data.
GLMM Statistics: significant fixed effects are identified as: asignificant Group × Time interaction; bsignificant effect of Time; and csignificant effect of Group. Refer to text for model statistics and estimated marginal means between relevant factor contrasts.
AM, morning/baseline fetal assessment; PM, afternoon fetal assessment; HR, heart rate; STV, short-term variation; bpm, beats per minute; n, total number; ms, milliseconds; min, minutes.
†
Maternally-perceived fetal movements per hour (adjusted from ~50 min).