Figure 4.

TcGTs are temporally expressed throughout neurogenesis in a cell type–specific manner, show protein-coding potential, and potentially drive transcript expression. (A) Heatmap showing the proportion of samples per developmental stage the 68 TcGTs (from Fig. 3D) were detected in the BrainSpan data set, regardless of region. Cell type–specific ATAC-seq overlaps and protein-coding potential determined via in silico translation are shown to the right of the plot. Bold indicates novel transcripts not annotated in Ensembl. See also Supplemental Table S8. (B) Dot plots showing the gene expression level per stage for the specified gene for samples in which the TcGT was detected (red) and in which it was not (blue) from the Cardoso data set in comparison to A. Dashed line represents birth at stage 6.