Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 16;9:721105. doi: 10.3389/fchem.2021.721105

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Pal and Rakshit.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A) Confocal Fluorescence microscope images of time-dependent targeted DNA origami uptake. MDA-MB-468 cells were incubated with 10 pM of targeted DNA origami structures for 6, 12, and 24 h respectively, suggesting a higher cellular uptake with increasing time; Cell nucleus and membrane were stained with Hoechst® 33342 (blue) and wheat germ agglutinin, AF488 conjugate (green), respectively. (B, C) Flow cytometry-based measurement also showed enhanced intracellular fluorescence with increasing time. (D) WST1 Cell viability assay validated no significant toxicity up to 100 pM targeted DNA origami.