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. 2021 Aug 16;8:718055. doi: 10.3389/fcvm.2021.718055

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Copyright © 2021 Feng, Zhao, Xu, Xing, Yang, Ma, Qi, Zhang and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histological characterization of infarcted hearts. (A) Photographs of rat hearts harvested 28 days after implantation. (B) Masson's trichrome staining of the heart transections of rats. (C–F) Immunohistochemical staining and quantitative analysis of Col1a1 to detect cardiac fibrosis of myocardial tissues. Left ventricle wall thickness (D) and collagen volume fraction (CVF%) (E) of infarcted area. Data are mean ± SEM from three independent experiments. ^**P < 0.01.