Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 16;8:718055. doi: 10.3389/fcvm.2021.718055

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Feng, Zhao, Xu, Xing, Yang, Ma, Qi, Zhang and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

rGO decreased the secretion of Col I and Co1 III in cardiofibroblasts (CFs) through Yap/Taz-TGFβ1/Smads signaling. (A,B) Effect of rGO on the secretion of Col I and Co1 III by CFs after angiotensin II (Ang II) treatment; CFs were treated with Ang II and rGO at 50 or 100 μg/ml for 24 h. (C–E) Effect of rGO on the mRNA expression of Col I, Co1 III and TGF-β1. (F–K) Western blot analysis of the signaling pathway (YAP, TAZ, TGF-b1, Smad3, Smad4 and Col I) in CFs stimulated with Ang II and with rGO. Data are mean ± SEM from three independent experiments. *P < 0.05, **P < 0.01.