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. 2021 Aug 16;11:710545. doi: 10.3389/fonc.2021.710545

Table 4.

Characteristics and outcomes of six patients with relapse.

Patient No. Diagnosis High-Risk Factor at Diagnosis Disease Status at HSCT Starting Time of Decitabine (days) Cycles of Decitabine Reason for Discontinuation of Decitabine Bone Marrow Results at Relapse Time From HSCT to Relapse (days) Treatment After Relapse Overall Survival (days)
16 B-ALL Ph+
WBC >100×109/L
CR1 63 5 Withdrew consent Marrow blast 97.6%
T315I mutation
276 DLI + chemotherapy 433
2 B-ALL CD10 CR1 97 8 Completed study Extramedullary 551 Chemotherapy; TBI;
DLI
725
17 B-ALL Ph+
Age >35
CR2 110 2 Relapse Marrow blast 42%
T315I mutation
168 Automatic discharge 213
3 B-ALL No CR2 84 3 Relapse Marrow blast 49.6% 205 Automatic discharge 244
30 T-LBL Leukemic phase; WBC>100×109/L CR1 93 3 Relapse Extramedullary 156 Chemotherapy >205
18 B-ALL Ph+ CR1 60 5 Relapse Marrow blast 16.4% 221 Chemotherapy >427

WBC, white blood cell; CR, complete remission; DLI, donor lymphocyte infusion; HSCT, hematopoietic stem cell transplantation.