Effects of baicalin on serum inflammatory factors and renal oxidative stress factors in DN rats. The DN rats are administered with 50 mg/kg (Baicalin-L), 100 mg/kg (Baicalin-M), and 200 mg/kg (Baicalin-H) baicalin for 4 weeks by gavage. (a) the expression of inflammatory factors TNF-α, IL-1β, and IL-6 in the serum of rats in each group; (b) the activities of LDH, SOD, and MDA in the renal tissue of rats in each group; ##
p < 0.01 vs Control group; *p < 0.05, **p < 0.01, and ***p < 0.001 vs DN group.