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DANT preserves lymphatic contractions in isolated rat mesenteric LVs exposed to DOX. (A) Rhythmic contractions of a single LV exposed to increasing concentrations of DOX (0.5–20 μmol/L). DOX progressively inhibited rhythmic contractions and reduced end-diastolic diameter. (B) Incubation with DANT (3 μmol/L) prevented DOX-induced inhibition of contractions.
