Table 2. Summary of longitudinal ctDNA detection results and clinical recurrence.
| Patient no. | ctDNA detection (months post-surgery) | Clinical recurrence | Recurrence recognition time (months) | Adjuvant therapy | Recurrence detection method | |||
|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 3 | 6 | |||||
| LB-001 | O | NA | O | O | Recur | 6 | RT | Clinic, CT |
| LB-002 | O | O | O | O | Recur | 8.5 | - | Clinic, pathology |
| LB-003 | O | - | - | - | Recur | 12 | CCRT | Clinic, MRI |
| LB-004 | O | - | - | - | - | - | - | - |
| LB-005 | O | - | NA | - | - | - | - | - |
| LB-006 | O | - | - | O | Recur | 6 | CCRT | MRI |
| LB-007 | O | O | NA | NA | Recur | 7.5 | CCRT | MRI, CT |
| LB-008 | O | O | O | O | Recur | 6 | - | MRI, CT |
| LB-009 | O | O | - | - | - | - | - | - |
| LB-010 | O | - | - | - | - | - | RT | - |
| LB-011 | O | NA | - | - | - | - | - | - |
In five out of six patients, locoregional recurrences were detected earlier with liquid biopsy than with conventional methods. NA: not available.