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. 2021 Aug 16;15:638114. doi: 10.3389/fnint.2021.638114

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Copyright © 2021 Sun, Wang, Han, Meng, Han and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Differentially expressed miRNA-target network. Blue circular nodes are downregulated mRNAs; Red circular nodes are upregulated mRNAs; Green triangles are downregulated miRNAs; Orange triangles represent upregulated miRNAs. (B) The biological processes enriched by miRNAs. The changes in bubble color from blue to red indicate that the correlation is significant from low to high. Dot size GeneRatio is gene proportion. The size of the gene specific proportion indicates the proportion of the enrichment item.