Table 1.

Patient and Tumor Characteristics

	Total (N=59)
Age^
Median (min, max)	60.7 (37.4, 90.5)
	N (%)
<65	35 (59.3)
≥65	24 (40.7)
Sex
Female	29 (49.2)
Male	30 (50.8)
Smoking*
No	29 (50.0)
Yes	29 (50.0)
Histology
Adenocarcinoma	56 (94.9)
Squamous cell	3 (5.1)
PS^
0	36 (61.0)
1	21 (35.6)
2	1 (1.7)
3	1 (1.7)
Brain metastases^
No	51 (86.4)
Yes	8 (13.6)

Notes: *Data not available for all subjects. Missing values: Smoking= 1. ^ At afatinib administration.

Abbreviation: PS, Performance status.