Table 1:
Drugs in Experimental Interventions related to COVID-19 in Phase 4 of Data from: ClinicalTrials.gov Searched as: “COVID-19”, “2019-nCoV”, “novel coronavirus 2019”, “SARS-CoV-2”, “coronavirus disease 2019.
| Clinical Trails | |||
|---|---|---|---|
| Drug(s) or Treatment(s) | ClinicalTrials.gov Identifier | Action (s) | PubChem Compound ID (CID) or Reference(s) |
| Hydroxychloroquine | NCT04359615 [62] | Immunosuppressive | CID=3652 [63] |
| NCT04359316 [64] | Anti-autophagy | ||
| NCT04343768 [65] | Anti-inflammatory | ||
| NCT04350671 [66] | Antirheumatologic | ||
| NCT04350684 [67] | Anti-malarial | ||
| NCT04355026 [68] | |||
| NCT04351919 [69] | |||
| NCT04351191 [70] | |||
| NCT04346667 [71] | |||
| NCT04334967 [72] | |||
| NCT04330495 [73] | |||
| NCT04341493 | |||
| NCT04338906 [74] | |||
| NCT04363866 [75] | |||
| Favipiravir | NCT04359615 [62] | Antiviral | CID=492405 [76] |
| Azithromycin |
NCT04359316[64] NCT04351919 [69] |
Antibiotic | CID=447043 [77] |
| Lopinavir / Ritonavir Or Ritonavir |
NCT04343768 [65] NCT04350671 [66] NCT04350684 [67] NCT04345276 [78] NCT04291729 [79] NCT04255017 [80] |
Antiviral | CID=11979606 [81] CID=392622 [82] |
| Interferon-βInterferon-β 1b, or PegIFN-α-2b |
NCT04343768 [65] NCT04350671 [66] NCT04350684 [67] NCT04291729 [79] NCT04254874 [83] |
Antiviral Antiproliferative Immunomodulator | Isaacs Lindenmann, et al. [84] |
| Lenalidomide | NCT04361643 [85] | Immunomodulator Antineoplastic | CID=216326 [86] |
| Arbidol (Umifenovir) |
NCT04350684 [67] NCT04255017 [80] NCT04254874 [83] NCT04260594 [87] |
Antiviral | CID=131411 [88] |
| Tetrandrine | NCT04308317 [89] | Immunosuppressive Antiproliferative Antioxidant | CID=73078 [90] |
| Chloroquine Sulfate | NCT04331600 [91] | Anti-malarial Anti-inflammatory | CID=91441 [92] |
| Carrimycin | NCT04286503 [93] | Antibiotic | Wang, et al. [49] |
| Ganovo (Danoprevir) |
NCT04345276 [78] NCT04291729 [79] |
Antiviral | CID=11285588 [94] |
| Bromhexine | NCT04355026 [68] | Expectorant Mucolytic | CID=2442 [95] |
| Thiazide or Thiazide-like diuretics | NCT04330300 [96] | Antihypertensive | Kjeldsen, et al. [97] |
| Calcium Channel Blockers | NCT04330300 [96] | Antihypertensive | Tocci, et al. [98] |
| Dexmedetomidine | NCT04350086 [99] | Analgesic Anxiolytic Sedative | CID=5311068 |
| Valsartan (Diovan) | NCT04335786 [100] | Antihypertensive | CID=60846 [101] |
| Sevoflurane | NCT04359862 [102] | Anesthetic | CID=5206 [103] |
| Oseltamivir | NCT04255017 [80] | Antiviral | CID=65028 [104] |
| Linagliptin | NCT04341935 | Dipeptidyl peptidase inhibitor | 4CID=10096344 [105] |
| Treatment for Diabetes Type 2 | |||
| Methylprednisolone | NCT04263402 [106] | Anti-inflammatory Immunosuppressive Neuroprotective Antiemetic Adrenergic | CID=6741 [107] |
| Ibuprofen | NCT04334629 [108] | Anti-inflammatory Analgesic Antipyretic | CID=3672 [109] |
| Nitazoxanide | NCT04341493 | Antiprotozoal Antiviral Antibiotic | CID=41684 [110] |
| Camostat Mesilate | NCT04338906 [74] | Anti-inflammatory | Gibo, et al. [111] |
| Budesonide | NCT04355637 [112] | Anti-inflammatory/ Bronchodilator | CID=5281004 [113] |
| Losartan | NCT04340557 | Antihypertensive | CID=3961 [114] |
| Oral nutrition supplement enriched in eicosapentaenoic acid, gamma-linolenic acid and antioxidants | NCT04323228 [115] | Anti-inflammatory Anti-oxidant | Gadek, et al., Singer, et al., Pontes-Arruda et al. [116–129] |