TABLE 3.
Combined effects of rs2296241-A, rs2248359-T, and rs4646536-T on NAFLD risk.
| Variables | Controls [n (%)] | NAFLD cases [n (%)] | NAFLD prevalence (%) | OR (95% CI) | p-valuea |
| 0 | 244 (12.8) | 113 (10.1) | 31.7 | 1.00 (ref.) | |
| 1–3 | 1,310 (68.6) | 773 (69.4) | 37.1 | 1.348 (1.016, 1.788) | 0.039 |
| 4–6 | 355 (18.6) | 228 (20.5) | 39.1 | 1.438 (1.038, 1.993) | 0.029 |
| Trend | ptrend = 0.049b | ||||
| 0 | 244 (12.8) | 113 (10.1) | 31.7 | 1.00 (ref.) | |
| 1–6 | 1,665 (87.2) | 1,001 (89.9) | 37.5 | 1.368 (1.035, 1.807) | 0.028 |
Variables are numbers of combined unfavorable alleles (rs2296241-A, rs2248359-T, and rs4646536-T).
Bold type indicates statistically significant results.
aLogistic regression analyses adjusted for gender, age, AST, ALT, GGT, TG, TC, and HDL-C.
bptrend-Value was analyzed by Cochran-Armitage trend test.