Table 2.
Amino acid variation among SP-A1 and SP-A2 variants.
| †AA#/SNP id | 9/rs139899873 | 19/rs1059047 | 50/rs1136450 | 66 | 73 | 81 | 85 | 91/rs1136452 | 219/rs4253527 | 223/rs397728201 |
|---|---|---|---|---|---|---|---|---|---|---|
| SP-A1 | ||||||||||
| 6A | Asn (AAC) | Ala (GCG) | Leu (CTC) |
SP-A1 amino acid gene-specific
differences ( Table 1 ) |
Pro (CCT) | Arg (CGG) | Gln (CAG) | |||
| 6A2 | Asn (AAC) | Val (GTG) | Val (GTC) | Pro (CCT) | Arg (CGG) | Gln (CAG) | ||||
| 6A3 | Asn (AAC) | Val (GTG) | Leu (CTC) | Pro (CCT) | Arg (CGG) | Gln (CAG) | ||||
| 6A4 | Asn (AAC) | Val (GTG) | Leu (CTC) | Pro (CCT) | Trp (TGG) | Gln (CAG) | ||||
| 6A5 | Asn (AAC) | Ala (GCG) | Leu (CTC) | Pro (CCT) | Trp (TGG) | Gln (CAG) | ||||
| †AA#/SNP id | 9/rs1059046 | 19/rs201847938 | 50/rs192907309 | 66 | 73 | 81 | 85 | 91/rs17886395 | 219/rs571610539 | 223/rs1965708 |
| SP-A2 | ||||||||||
| 1A | Thr (ACC) | Ala (GCG) | Val (GTC) |
SP-A2 amino acid gene-specific differences
( Table 1 ) |
Pro (CCT) | Arg (CGG) | Gln (CAG) | |||
| 1A0 | Asn (AAC) | Ala (GCG) | Val (GTC) | Aln (GCT) | Arg (CGG) | Gln (CAG) | ||||
| 1A1 | Thr (ACC) | Ala (GCG) | Val (GTC) | Aln (GCT) | Arg (CGG) | Lys (AAG) | ||||
| 1A2 | Thr (ACC) | Ala (GCG) | Val (GTC) | Aln (GCT) | Arg (CGG) | Gln (CAG) | ||||
| 1A3 | Asn (AAC) | Ala (GCG) | Val (GTC) | Aln (GCT) | Arg (CGG) | Lys (AAG) | ||||
| 1A5 | Thr (ACC) | Ala (GCG) | Val (GTC) | Pro (CCT) | Arg (CGG) | Gln (CAG) | ||||
†Amino acid (AA) position is based on the precursor molecule that includes the signal peptide.
Red and Green area indicate gene specific amino acids.
Underlines indicates the variable nucleotide.