Table 1.
Demographic characteristics of initially amyloid-negative subjects at baseline and last follow-up.
| All | Converter | Stable | |
| n | 23 | 7 | 16 |
| Female | 12 (52.1%) | 6 (85.7%)∗ | 6 (37.5%) |
| Age, yr | 67.9 ± 5.0 | 69.2 ± 3.2 | 67.3 ± 5.6 |
| Education, yr | 13.3 ± 2.5 | 12.8 ± 3.1 | 13.6 ± 2.2 |
| APOE ε4 carriers | 6 (26.0%) | 4 (57.1%)∗ | 2 (12.5%) |
| at baseline | |||
| MMSE | 28.2 ± 2.3 | 27.5 ± 2.7 | 28.5 ± 2.1 |
| CDR | 0.15 ± 0.24 | 0.21 ± 0.27 | 0.13 ± 0.22 |
| CDR SB | 0.22 ± 0.39 | 0.43 ± 0.61 | 0.13 ± 0.22 |
| Immediate rec | 12.2 ± 4.9 | 10.7 ± 4.6 | 12.9 ± 5.1 |
| Delayed rec | 9.0 ± 4.7 | 7.4 ± 5.0 | 9.8 ± 4.6 |
| at last follow-up | |||
| MMSE | 27.3 ± 3.7 (0.135) | 27.8 ± 3.9 (0.407) | 27.9 ± 2.1 (0.177) |
| CDR | 0.33 ± 0.47 (0.052) | 0.57 ± 0.53 (0.078) | 0.19 ± 0.25 (0.163) |
| CDR SB | 0.96 ± 2.53 (0.135) | 1.57 ± 2.30 (0.151) | 0.31 ± 0.44 (0.082) |
| Immediate rec | 12.0 ± 5.7 (0.835) | 9.4 ± 3.8 (0.467) | 13.2 ± 5.1 (0.748) |
| Delayed rec | 9.6 ± 6.8 (0.584) | 6.5 ± 7.3 (0.701) | 11.0 ± 6.3 (0.315) |
| Follow-up, yr | 6.5 ± 1.4 | 7.3 ± 1.2 | 6.2 ± 1.4 |
APOE = apolipoprotein E, CDR = Clinical Dementia Rating, CDR SB = CDR sum of boxes, MMSE = Mini-Mental State Examination, n = number of subjects, rec = WMS-R recall scores, Data are presented as means ± SD.
∗
Fisher's exact test, P < .05, P value of paired t test between baseline and follow-up data is given in parenthesis.