Table 2.

Mendelian randomization estimates of rheumatoid arthritis on Graves’ disease.

Exposure	Method	OR	95% CI	P-value	MR-Egger intercept (P-value)	Statistical power
Rheumatoid arthritis	Inverse variance weighted	1.39	1.10–1.75	0.007		1
	MR-Egger	1.75	1.23–2.49	0.012	−0.10 (0.131)
	Weighted median	1.45	1.33–1.58	<0.001
Rheumatoid arthritis*	Inverse variance weighted	1.36	1.09–1.70	0.007		0.95
	MR-Egger	1.32	0.86–2.03	0.237	0.01 (0.869)
	Weighted median	1.51	1.36–1.68	<0.001

The two sets of SNPs associated with RA are independent.

*Previous summary data of rheumatoid arthritis from GWAS conveyed by Okada et al.