TABLE 5.

Effect of topical application of an ointment containing ethanolic leaf extract of C. gigantea leaves on wound contraction of the burn wound. Mean percentage of wound contraction ±SEM.

Groups	Treatment	4th day	8th day	12th day	16th day	Period of epithelization
Group 1	Control (simple ointment)	23.09 ± 1.15	33.00 ± 1.45	57.19 ± 0.83	65.18 ± 0.92	28.09 ± 0.47
Group 2	Standard (nitrofurazone) 0.2% w/w	28.12 ± 2.03***	53.02 ± 0.32***	73.07 ± 0.95***	81.38 ± 0.81***	22.93 ± 1.57***
Group 3	ECGLD 2% w/w	27.00 ± 0.95***	32.83 ± 2.76 ns	61.33 ± 0.99***	78.75 ± 1.71***	24.10 ± 1.00***
Group 4	ECGHD 4% w/w	25.25 ± 0.95 ns	44.17 ± 2.55***	50.78 ± 1.70***	70.67 ± 1.31***	25.30 ± 0.54***

ECGLD: extract of C. gigantea low dose; ECGHD: extract of C. gigantea high dose. n = 6 animals in each group. The treated groups are analyzed by two-way ANOVA for wound closure and -way ANOVA for the period of epithelization by comparing with the control group. ***p < 0.001, ns: not significant.