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Chemical structure of different natural compounds targeting host proteases. TMPRSS2 (VIII): aprotinin (123, PDB: 1BPI), tannic acid (25), and celastrol (31). CatL (IX): leupeptin (135), gallinamide A (136), panduratin A (138), nicolaidesin C (138), and grassypeptolide A-C (139–141).
