Table 3.
Simulated asymmetry of TFs concentrations (PTF = 0.72; polarity levels LBLIMP1, LIRF4, and LBCL6) in daughter cells after asymmetric division.
| Mode Ag division | ||||
|---|---|---|---|---|
| Asymmetric | Symmetric | |||
| Polarity level (LTF) | ||||
| Simulations | BLIMP1 (LBLIMP1) | IRF4(LIRF4) | BCL6 (LBCL6) | BLIMP1, IRF4, BCL6(LBLIMP1 = LIRF4 − LBCL6) |
| 1–3 | 1.0 | 1.0 | 0.5 | |
| 4–6 | 0.9 | 1.0 | 0.5 | |
| 7–9 | 0.75 | 1.0 | 0.5 | |
| 10–12 | 1.0 0.75 0.9 |
1.0 | 0.9 | 0.5 |
| 13–15 | 0.9 | 0.9 | 0.5 | |
| 16–18 | 0.75 | 0.9 | 0.5 | |
| 19–21 | 1.0 | 0.75 | 0.5 | |
| 22–24 | 0.9 | 0.75 | 0.5 | |
| 25–27 | 0.75 | 0.75 | 0.5 | |
TFs divide asymmetrically if Ag divides asymmetrically (PAg = PTF = 0.72; LAg = 1.0). In these 27 simulations, BCL6, IRF4, and BLIMP1 do not always cosegregate with same polarity levels.