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. 2021 Aug 17;11:692390. doi: 10.3389/fonc.2021.692390

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Copyright © 2021 Zhang, Fu, Ding, Zhu, Zhao, Song, Huang, Chen, Yang, Zhang, Hu, Ni and Ding

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Reelin was upregulated in CAFs compared with TCs derived from OSCC and other several cancers. Enhanced level of RELN^CAF compared with RELN^TC in breast cancer (A), pancreatic cancer (B), and rectal carcinoma (C) using the GEO database. Representative immunohistochemistry staining of Reelin in OSCC, according to TCs, FLCs and TILs (D). The IHC score of Reelin^TC and Reelin^FLC in OSCC (E). **** denoted that differences were considered statistically significant with p < 0.0001.