Table 1.
Association between Reelin and clinicopathological characteristics in OSCC patients.
| Characteristics | TCs | FLCs | TILs | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Low (%) | High (%) | χ 2 | p | n | Low (%) | High (%) | χ 2 | p | n | Low (%) | High (%) | χ 2 | p | |
| Sex | |||||||||||||||
| Female | 29 | 17 (58.6) | 12 (41.4) | 0.331 | 0.565 | 29 | 16 (55.2) | 13 (44.8) | 0.645 | 0.422 | 29 | 17 (58.6) | 12 (41.4) | 1.197 | 0.274 |
| Male | 46 | 30 (65.2) | 16 (34.8) | 46 | 21 (45.7) | 25 (54.3) | 46 | 21 (55.3) | 25 (67.6) | ||||||
| Age | |||||||||||||||
| <60 | 36 | 21 (58.3) | 15 (41.7) | 0.556 | 0.456 | 36 | 15 (41.7) | 21 (58.3) | 1.628 | 0.202 | 36 | 21 (58.3) | 15 (41.7) | 1.628 | 0.202 |
| ≥60 | 39 | 26 (66.7) | 13 (33.3) | 39 | 22 (56.4) | 17 (43.6) | 39 | 17 (43.6) | 22 (56.4) | ||||||
| Smoking | |||||||||||||||
| No | 33 | 16 (48.5) | 17 (51.5) | 2.082 | 0.149 | 33 | 17 (51.5) | 16 (48.5) | 0.012 | 0.912 | 33 | 17 (51.5) | 16 (48.5) | 0.194 | 0.660 |
| Yes | 22 | 15 (68.2) | 7 (31.8) | 22 | 11 (50.0) | 11 (50.0) | 22 | 10 (45.5) | 12 (54.5) | ||||||
| Not achieved | 20 | 20 | 20 | ||||||||||||
| T Stage | |||||||||||||||
| 1–2 | 60 | 38 (63.3) | 22 (36.7) | 0.760 | 60 | 31 (51.7) | 29 (48.3) | 0.13 | 0.719 | 60 | 29 (48.3) | 31 (51.7) | 0.745 | 0.388 | |
| 3–4 | 13 | 9 (69.2) | 4 (30.8) | 13 | 6 (46.2) | 7 (53.8) | 13 | 8 (61.5) | 5 (38.5) | ||||||
| Not achieved | 2 | 2 | 2 | ||||||||||||
| N Stage | |||||||||||||||
| No | 36 | 19 (52.8) | 17 (47.2) | 4.172 | 0.041* | 36 | 24 (66.7) | 12 (33.3) | 7.258 | 0.007* | 36 | 15 (41.7) | 21 (58.3) | 2.311 | 0.128 |
| Yes | 37 | 28 (75.7) | 9 (24.3) | 37 | 13 (35.1) | 24 (64.9) | 37 | 22 (59.5) | 15 (40.5) | ||||||
| Differentiation | |||||||||||||||
| Well | 16 | 7 (43.8) | 9 (56.3) | 2.942 | 0.086 | 16 | 9 (56.3) | 7 (43.8) | 0.319 | 0.572 | 16 | 8 (50.0) | 8 (50.0) | 0.015 | 0.903 |
| Moderate to poor | 58 | 39 (67.2) | 19 (32.8) | 58 | 28 (48.3) | 30 (51.7) | 58 | 30 (51.7) | 28 (48.3) | ||||||
| Not achieved | 1 | 1 | 1 | ||||||||||||
| WPOI | |||||||||||||||
| 1–3 | 28 | 18 (64.3) | 10 (35.7) | 0.003 | 0.955 | 28 | 18 (64.3) | 10 (35.7) | 4.506 | 0.034* | 28 | 12 (42.9) | 16 (57.1) | 0.935 | 0.334 |
| 4–5 | 44 | 28 (63.6) | 16 (36.4) | 44 | 17 (38.6) | 27 (61.4) | 44 | 24 (54.5) | 20 (45.5) | ||||||
| Not achieved | 3 | 3 | 3 | ||||||||||||
TCs, tumor cells; FLCs, fibroblast-like cells; TILs, tumor-infiltrating lymphocytes; WPOI, worst pattern of invasion; χ2, Pearson’s chi-squared test.
*Denotes that differences were considered statistically significant with p < 0.05.