Table 1.
Demographics and baseline characteristics of patients infected with SFTSV in Jeju, South Korea, from 2013 to 2019 (n=54).
| Variables | All patients (n = 54) | Patients with nonfatal disease (n = 47) | Patients with fatal disease (n = 7) | p-value |
|---|---|---|---|---|
| Age ± SD (years) | 62.8 ± 14.3 | 61.4 ± 14.4 | 72.0 ± 9.9 | 0.046 |
| Sex, n (%) | ||||
| Men, n (%) | 31 (58.5) | 25 (54.3) | 6 (85.7) | 0.12 |
| CCI ± SD | 0.4 ± 0.7 | 0.3 ± 0.7 | 0.9 ± 0.9 | 0.04 |
| Febrile sensation, n (%) | 49 (92.5) | 45 (97.8) | 4 (57.1) | 0.001 |
| Myalgia, n (%) | 21 (39.6) | 25 (54.3) | 6 (85.7) | 0.02 |
| Diarrhea, n (%) | 22 (41.5) | 19 (41.3) | 3 (42.9) | 0.03 |
| Hemoptysis, n (%) | 2 (3.8) | 1 (2.2) | 1 (14.3) | 0.04 |
| Dyspnea, n (%) | 2 (3.8) | 0 (0) | 2 (28.6) | 0.001 |
| Mean time from symptom onset to diagnosis ± SD |
5.6 ± 3.1 | 5.8 ± 3.2 | 5.4 ± 2.9 | 0.79 |
| Mean body temperature ± SD (°C) |
38.6 ± 0.8 | 38.6 ± 0.8 | 38.1 ± 0.9 | 0.04 |
| ANC ± SD (cells/μL) | 1,403.0 ± 1,307.1 | 1,373.2 ± 1,308.8 | 1,621.8 ± 1,395.5 | 0.67 |
| Platelet count ± SD (/μL) | 57,682.6 ± 28,924.2 | 5,963.0 ± 34,028.4 | 44,700.0 ±8,657.9 | 0.24 |
| CRP ± SD (mg/dL) | 0.9 ± 1.7 | 0.82 ± 1.5 | 1.8 ± 2.6 | 0.16 |
| AST ± SD (IU/L) | 182.6 ± 301.3 | 122.8 ± 140.7 | 575.6 ± 656.5 | <0.001 |
| ALT ± SD (IU/L) | 77 ± 87.3 | 64.0 ± 55.2 | 162.3 ± 182.8 | 0.004 |
| CK ± SD (IU/L) | 1,069.6 ± 1,741.7 | 9,45.1 ± 1592.3 | 1,834.3 ± 2,496.0 | 0.21 |
| LDH ± SD (IU/L) | 1,083.6 ± 1,303.6 | 828.0 ± 631.7 | 3,042.7 ± 2,921.6 | <0.001 |
| MODS ± SD | 4.43 ± 4.3 | 3.0 ± 1.8 | 13.7 ± 4.2 | <0.001 |
| Viral load ± SD (copies/mL) |
98,022,220.9 ± 702,692,683.2 | 403,658.3 ± 795,822.0 | 725,570,123.6 ± 1,914,726,379.0 | 0.0019 |
Values are presented as the mean ± standard deviation. SFTSV, severe fever with thrombocytopenia syndrome virus; CCI, Charlson Comorbidity Index; ANC, absolute neutrophil count; CRP, c-reactive protein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CK, creatinine kinase; LDH, lactate dehydrogenase; MODS, multiorgan dysfunction score.