Table 3-2.
Kinetics of IL-6 and IL-10 concentrations, viral load, and neutralizing antibody titers in patients with nonfatal severe disease.
| Patients | Age (years) /Sex | Date | Severity | Outcome | IL-6 | IL-10 | Viral load (copies/mL) | FRNT50 titer (11) |
|---|---|---|---|---|---|---|---|---|
| P49-18 | 81/F | *Jun-12-18 | Severe | Recovered | 22.2 | 40.8 | 1,222,514.26 | 3.401 |
| Jun-14-18 | 23.5 | 28.7 | 18,307.96 | 2.171 | ||||
| Jun-16-18 | 18.8 | 6.7 | 4,798.72 | 0.6024 | ||||
| Jun-18-18 | 13 | 2.2 | 2,785.74 | 9.89 | ||||
| P64-19 | 64/M | *Aug-12-19 | Severe | Recovered | 5.6 | 5.6 | 48,766.65 | 0 |
| Aug-14-19 | 2.5 | 1.5 | 3,266.81 | 0 | ||||
| Aug-16-19 | 2.4 | 1 | 1,217.66 | 0 | ||||
| P66-19 | 60/F | *Aug-28-19 | Severe | Recovered | 3.9 | 3.8 | 798,839.84 | 10.25 |
| Aug-30-19 | 3.2 | 2.6 | 34,353.24 | 5.857 | ||||
| P70-19 | 70/F | *Oct-11-19 | Severe | Recovered | 7.1 | 7.1 | 101,288.97 | 13.53 |
| Oct-22-19 | 23.6 | 2.9 | Undetermined | 34.82 |
Unit: pg/ml, *The hospitalization and sampling date; P, positive; N, negative; FRNT50, 50% focus reduction neutralization test.