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. 2021 Aug 17;11:677939. doi: 10.3389/fonc.2021.677939

Table 4.

Change levels of inflammatory factors,hemorheology,lipid and immunologic factors in vivo (n=45 each group).

Groups Inflammatory factors
TNF- (ng/ml) IL-6 (μmol/L) IL-8 (μmol/L)
Start 6 months Start 6 months Start 6 months
Treatment 12.31 ± 3.1 3.48 ± 1.12 107.39 ± 31.02 62.71 ± 39.47 112.92 ± 81.66 61.67 ± 31.94
Control 12.85 ± 2.8 15.78 ± 2.93 106.91 ± 18.40 103.54 ± 22.74 111.74 ± 54.83 114.58 ± 89.43
P value 0.76 0.00 1.00 0.00 1.00 0.00
Groups  Hemorheological indices (mPa.s)
Low cut whole blood viscosity (1/S) Medium cut whole blood viscosity (30/S) High cut whole blood viscosity (200/S)
Start 6 months Start 6 months Start 6 months
Treatment 17.55 ± 1.5 16.28 ± 1.49 4.83 ± 0.13 4.66 ± 0.21 3.94 ± 0.12 3.67 ± 0.21
Control 17.65 ± 1.74 17.86 ± 1.68 4.81 ± 0.18 4.86 ± 0.19 3.92 ± 0.15 3.99 ± 0.16
P value 1.00 0.00 0.95 0.00 0.94 0.00
Groups  Hemorheological indices (mPa.s)
plasma viscosity  Reduced viscosity of whole blood (high cut) Reduced viscosity of whole blood (low cut)
Start 6 months Start 6 months Start 6 months
Treatment 1.55 ± 0.14 1.39 ± 0.11 5.53 ± 0.39 5.37 ± 0.21 41.43 ± 4.06 39.39 ± 3.75
Control 1.55 ± 0.11 1.57 ± 0.1 5.53 ± 0.38 5.61 ± 0.41 41.94 ± 3.95 42.18 ± 3.95
P value 0.99 0.000 0.99 0.009 0.93 0.005
Groups  Lipid indices (mmol/L)
TC TG LDL
Start 6 months Start 6 months Start 6 months
Treatment 5.05 ± 0.6 4.48 ± 0.57 2.75 ± 0.54 1.55 ± 0.21 3.17 ± 0.29 2.84 ± 0.26
Control 4.91 ± 0.67 4.96 ± 0.67 2.66 ± 0.56 2.82 ± 0.39 3.13 ± 0.34 3.19 ± 0.26
P value 0.72 0.002 0.78 0.000 0.91 0.00
Groups  Lipid indices (mmol/L) T cell immunologic indices (%)
HDL CD3 CD4
Start 6 months Start 6 months Start 6 months
Treatment 1.57 ± 0.16 1.71 ± 0.15 59.94 ± 6.85 64.47 ± 6.00 36.29 ± 7.59 39.59 ± 6.36
Control 1.55 ± 0.14 1.52 ± 0.17 60.6 ± 6.91 59.2 ± 6.81 36.33 ± 8.51 32.13 ± 6.61
P value 0.93 0.00 0.97 0.001 0.99 0.00
Groups T cell immunologic indices (%) B cell immunologic indices
CD8 CD4/CD8 IgM (g/L)
Start 6 months Start 6 months Start 6 months
Treatment 24.06 ± 7.85 23.18 ± 7.64 1.72 ± 0.69 1.91 ± 0.73 1.08 ± 0.39 1.39 ± 0.43
Control 24.47 ± 7.42 25.47 ± 7.16 1.81 ± 1.22 1.38 ± 0.56 1.06 ± 0.3 1.09 ± 0.37
P value 0.99 0.47 0.96 0.016 0.99 0.001
Groups  B cell immunologic indices (g/L)  Complement indices (ng/ml)
IgA IgG C3
Start 6 months Start 6 months Start 6 months
Treatment 1.73 ± 0.43 2.17 ± 0.47 10.91 ± 1.46 12.25 ± 1.55 0.88 ± 0.15 0.93 ± 0.16
Control 1.73 ± 0.48 1.8 ± 0.45 10.85 ± 1.6 11.04 ± 1.62 0.89 ± 0.14 0.88 ± 0.14
P value 0.99 0.001 0.99 0.002 0.99 0.38
Groups Complement indices (ng/ml)
C4
Start 6 months
Treatment 0.22 ± 0.05 0.27 ± 0.06
Control 0.22 ± 0.06 0.23 ± 0.06
P value 0.99 0.007