Table III.
Information on potential targets and topological properties of Chuanxinlian against cerebral ischemia.
| No. | UniProt ID | Gene name | Protein name | Degree | Betweenness |
|---|---|---|---|---|---|
| 1 | O14920 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | 18 | 0.00467253 |
| 2 | P00734 | F2 | Coagulation factor II, thrombin | 11 | 0.00838562 |
| 3 | P00747 | PLG | Plasminogen | 15 | 0.05091082 |
| 4 | P01375 | TNF | Tumor necrosis factor | 23 | 0.19812513 |
| 5 | P03372 | ESR1 | Estrogen receptor 1 | 6 | 0.01264776 |
| 6 | P05121 | SERPINE1 | Serpin family E member 1 | 8 | 0.00336983 |
| 7 | P07550 | ADRB2 | Adrenoceptor beta 2 | 7 | 0.01043808 |
| 8 | P08069 | IGF1R | Insulin-like growth factor 1 receptor | 5 | 0.00441784 |
| 9 | P08172 | CHRM2 | Muscarinic acetylcholine receptor M2 | 6 | 0.00606293 |
| 10 | P08253 | MMP2 | Matrix metallopeptidase 2 | 7 | 0.01000518 |
| 11 | P11712 | CYP2C9 | Cytochrome P450 family 2 subfamily C member 9 | 7 | 0.04508112 |
| 12 | P13726 | F3 | Coagulation factor III, tissue factor | 5 | 0.00583017 |
| 13 | P14780 | MMP9 | Matrix metallopeptidase 9 | 9 | 0.04962157 |
| 14 | P25116 | F2R | Coagulation factor II thrombin receptor | 11 | 0.00838562 |
| 15 | P28482 | MAPK1 | Mitogen-activated protein kinase 1 | 19 | 0.21744713 |
| 16 | P30556 | AGTR1 | Angiotensin II receptor type 1 | 16 | 0.0567444 |
| 17 | P33261 | CYP2C19 | Cytochrome P450 family 2 subfamily C member 19 | 6 | 0.0237056 |
| 18 | P35354 | PTGS2 | Prostaglandin-endoperoxide synthase 2 | 8 | 0.12466034 |
| 19 | P37231 | PPARG | Peroxisome proliferator-activated receptor gamma | 5 | 0.04858176 |
| 20 | P42574 | CASP3 | Caspase-3 | 9 | 0.00262056 |
| 21 | Q07869 | PPARA | Peroxisome proliferator-activated receptor alpha | 7 | 0.02624386 |
| 22 | Q9HBW0 | LPAR2 | Lysophosphatidic acid receptor 2 | 13 | 0.01747176 |