Figure 3.

Proteasome inhibitors decrease paclitaxel-induced cell cycle arrest and apoptosis of nasopharyngeal carcinoma cells. (A) Proteasome inhibitors (PS341 and MG132) significantly reduced the paclitaxel-induced G₂/M phase arrest at 24 h. The data are presented as the mean ± SD (n=3) and were analyzed using two-way ANOVA followed by Tukey's post hoc test. ^*P<0.05. (B) Proteasome inhibitors significantly reduced paclitaxel-induced apoptosis. The data are presented as the mean ± SD (n=3) and were analyzed using one-way ANOVA followed by Tukey's post hoc test. ^*P<0.05. NC, negative control; PS341, bortezomib; PTX, paclitaxel.