. 2021 Aug 17;11:683876. doi: 10.3389/fonc.2021.683876

Table 5.

Pathological diagnosis and p16 methylation of SM biopsies.

No.	Direction		The distance to the tumor border (CM)^a
No.	Direction		1	2	3	4	5	6
1	O	Diag	MGD	N	N	N	N
1	O	P16m	+	–	+	–	–
2	O	Diag	HGD	N	mGD	N	N	N
2	O	P16m	+	–	+	–	+	+
3	O	Diag	HGD	N	N	N
	O	P16m	–	–	+	–
	A	Diag	MGD	N	N	N
	A	P16m	+	–	–	–
4	O	Diag	N	N	N
	O	P16m	+	+	+
	A	Diag	N	N	N	N	N
	A	P16m	+	+	–	–	–
5	O	Diag	N	N	N
5	O	P16m	+	+	–
6	O	Diag	N	mGD	N	N	N
6	O	P16m	+	+	–	+	–
7	O	Diag	N	N	N	N
	O	P16m	+	+	–	–
	A	Diag	N	N	N	N
	A	P16m	+	+	+	+
8	O	Diag	mGD	N	N	N
8	O	P16m	+	–	+	+
9	O	Diag	mGD	N	N	N
9	O	P16m	+	–	–	–

+, represents p16 methylated; -, represents p16 un-methylated. N, represents normal. ^aThe last sample of each row was obtained from the incisal edge. O, represents the oral edge and A, represents the anal edge.