Table 4.
The association of severe brain atrophy and traditional risk factors in predicting outcome.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| OR (95% CI) | p-value | Adjusted OR (95% CI) | p-value | |
| Severe atrophy | 0.47 (0.25, 0.85) | 0.015 | 0.33 (0.15, 0.70) | 0.005 |
| Age | 0.98 (0.96, 1.01) | 0.176 | ||
| Sex | 0.76 (0.41, 1.41) | 0.370 | ||
| Dyslipidemia | 1.55 (0.87, 2.76) | 0.134 | ||
| Diabetes mellitus | 0.79 (0.4, 1.51) | 0.484 | ||
| Hypertension | 1.42 (0.8, 2.58) | 0.241 | ||
| Atrial fibrillation | 1.53 (0.78, 2.98) | 0.208 | ||
| SBP | 1.00 (0.99, 1.02) | 0.460 | ||
| DBP | 1.00 (0.98, 1.01) | 0.727 | ||
| TIA | 0.47 (0.02, 3.27) | 0.508 | ||
| TOAST | 1.11 (0.78, 1.56) | 0.555 | ||
| Occlusion Sites | 0.90 (0.70, 1.15) | 0.392 | ||
| Thrombolysis treatment | 0.81 (0.40, 1.58) | 0.551 | ||
| Preonset mRS | 0.85 (0.39, 1.69) | 0.659 | ||
| Anesthesia | 1.13 (0.81, 1.57) | 0.463 | ||
| Onset to recanalization time | 0.99 (0.99, 1.00) | 0.591 | ||
| NIHSS baseline | 0.94 (0.91, 0.97) | <0.001 | 0.97 (0.93, 1.00) | 0.072 |
| PC-ASPECTS | 1.98 (1.59, 2.51) | <0.001 | 1.82 (1.44, 2.36) | <0.001 |
| mTICI | 1.68 (1.33, 2.19) | <0.001 | 1.80 (1.35, 2.50) | <0.001 |
| PC-CS score | 1.89 (1.43, 2.54) | <0.001 | 1.31 (1.09, 1.60) | 0.005 |
SBP, systolic blood pressure; DBP, diastolic blood pressure; TIA, transient ischemic attack; TOAST, Trial of ORG 10172 in Acute Stroke Treatment; PC-CS score, posterior circulation collateral system score; mTICI, modified thrombolysis in cerebral infarction; PC-ASPECTS, posterior circulation Alberta Stroke Program Early CT Score.