Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 12;15:718720. doi: 10.3389/fncel.2021.718720

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Ju, Yang, Jiang, Wang, Zhang, Zhao, Fang, Liao, Zheng, Li, Hou, Liang, Pan, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Decreased expression of myelin-related genes in 16p11.2^± striatum. (A) Decreased expression levels (in FPKM) of myelin-related genes in 16p11.2^± striatum. Total RNA was extracted from striatum tissues of 16p11.2^± mice (n = 4) and WT controls (n = 4) at P60 for RNAseq analysis. (B) Downregulated mRNA expression (relative to Gapdh) of Mag, Mog, Mbp, Plp1 and Cnpase in 16p11.2^± striatum as assessed by qRT-PCR (n = 4–6 mice). Data were analyzed with unpaired t tests (mean ± SEM, *p < 0.05, **p < 0.01). Mag, Myelin associated glycoprotein; Mog, Myelin oligodendrocyte glycoprotein; Mbp, Myelin basic protein; Plp1, Proteolipid protein 1; Cnpase, Cyclic nucleotide phosphodiesterase. FPKM, Fragments per kilobase of transcript per million mapped reads.