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. 2021 Aug 12;15:718720. doi: 10.3389/fncel.2021.718720

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Copyright © 2021 Ju, Yang, Jiang, Wang, Zhang, Zhao, Fang, Liao, Zheng, Li, Hou, Liang, Pan, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decreased SM and CerG1 species in 16p11.2^± striatum. (A,C) Heatmaps of SM (A) and CerG1 (C) species identified in the striatum of P60 16p11.2^± mice (n = 5) and WT controls (n = 6) by lipidomics analysis. The lipid species showing a significant change in level in 16p11.2^± striatum are written in red. (B,D) Charts of comparing the “red” SM (B) and CerG1 (D) species, indicating their decreased levels in the striatum of 16p11.2^± mice relative to WT controls (mean ± SEM, *p < 0.05/**p < 0.01 for unpaired t tests).